Myocardial infarction with non-obstructive coronary arteries: pathogenic patterns and diagnostic approach
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Abstract
The term MINOCA (Myocardial Infarction with Non-Obstructive Coronary Arteries) refers to pathological conditions where there is evidence of myocardial necrosis due to a lack of blood flow but no significant coronary lesions are seen on angiography. This is working diagnosis, which requires careful investigation to identify specific causes: plaque rupture, coronary dissection, vasospasm, microvascular dysfunction, thromboembolism, etc. Angiography alone, in most cases, does not lead to an etiological diagnosis. So additional techniques like intracoronary imaging and vasomotor function tests are important, especially in younger patients. This literature review demonstrates the main pathogenic patterns and diagnostic approachs for MINOCA patients.
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