Association of urinary albumin to creatinine ratio with different gender, age and clinical characteristics in patients with STEMI

Main Article Content

A. V. Bronyk
V. P. Ivanov
L. V. Rasputina

Abstract

The work method revealed the clinical course of STEMI depending on the functional state of the kidneys and ACR in the urine. Included were 286 patients with acute coronary syndromes, average age 62.8±9.8 years, after revascularization. Among the examined were 202 (70.6%) men and 84 (29.4%) women. It was established that 158 ​​places were classified as ACR <3, 92 individuals – ACR 3–30 mg/mmol and 36 – ACR >30 mg/mmol. Gender characteristics show that women were significantly more likely to belong to the group of ACR >30 mg/mmol, the distribution into different age gradations according to WHO (2015) showed that at the age of 25–44 all patients belonged to group 1 (ACR >3 mg/mmol ) and group 2 (ACR 3–30 mg/mmol). Among cases aged 75–89, there were significantly more persons with ACR >30 mg/mmol, p1–3=0.003; p2–3=0.01 the value of GFR calculated from the level of cystatin C in plasma according to the CKD-EPI formula Cystatin C shows significantly lower GFR in various categories of ACR based on GFR calculated on the basis of creatinine. With a decrease in GFR, the number of deficiencies that had gradations of ACR 3–30 and ACR >30 significantly increases. The clinical course of STEMI in the treatment of ACR over 30 is characterized by a longer history of hypertension and diabetes, a greater number of patients with diabetes, hereditary history of cardiovascular diseases, diagnosis of atrial fibrillation.

Article Details

Keywords:

acute myocardial infarction, acute coronary syndrome, revascularization, glomerular filtration rate, kidney function, creatinine, cystatin C, albumin/creatinine ratio in urine, cardiovascular diseases

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