Prevalence of Frailty syndrome in elderly hypertensive patients

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L. M. Yena
G. M. Khrystoforova
M. G. Akhaladze
O. G. Garkavenko


The aim – to determine the frequency and severity of Frailty syndrome in elderly patients with essential hypertension on the basis of geriatric instruments.
Materials and methods. 120 elderly patients with uncomplicated essential hypertension were investigated by conducting a survey on the questionnaire FRAIL and modified phenotype Frailty, Short Physical Performance Battery.
Results and discussion. The frequency of Frailty syndrome in elderly hypertensive’s significantly depend on the method used and was 17.2, 10.9 and 11.1 % while exploring the FRAIL questionnaire, the Frailty phenotype and the Short Physical Performance Battery, respectively. The predominant form of physical disorders was prefrail, its registration, depending on the method of diagnosis, varied from 20,2 % up to 68 %. The incidence of Frailty geriatric syndrome increased with age, it was more common in women than in men when measured by the FRAIL questionnaire and the Frailty phenotype.
Conclusions. In elderly patients with uncomplicated essential hypertension the registration of Frailty depends on the methods used. PreFrailty proved to be the predominant form of physical disorder.

Article Details


essential hypertension, elderly, geriatric syndromes, Frailty, FRAIL Scale, Frailty phenotype, physical status


Артеріальна гіпертензія. Оновлена та адаптована клінічна настанова, заснована на доказах (2012 р.) Робоча група з артеріальної гіпертензії УАК // Артеріальна гіпертензія.– 2012.– T 1, № 21.– С. 96–152.

Ена Л.М., Артеменко В.О., Христофорова А.М., Гаркаве­­­нко О.Г. Гериатрические синдромы // Проблемы старения и долголетия.– 2019.– Т. 28 (1).– С. 34–39.

Cкибчик В.А., Бабляк С.Д. Синдром старечої астенії (Frailty) – сучасна проблема геронтологічної медицини // Журнал «Артеріальна гіпертензія».– 2018.– T. 4 (60).– C. 12–18. doi:

Bergland A., Strand B.H. Norwegian reference values for the Short Physical Performance Battery (SPPB): the Tromsø Study // BMC Geriatr.– 2019.– Vol. 19 (1).– Р. 216. doi:

Bergman H., Ferrucci L., Guralnik J. et al. Frailty: an emerging research and clinical paradigm – issues and controversies // J. Gerontol. A Biol. Sci Med. Sci.– 2007.– Vol. 62.– Р. 731–737. doi:

Cosentino F., Grant P.J., Aboyans V. et al. ESC Scientific Document Group, 2019 ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force for diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and the European Association for the Study of Diabetes (EASD) // Eur. Heart J.– 2020.– Vol. 41 (2).– Р. 255–323. doi:

Fried L.P., Tangen C.M., Walston J. et al. Frailty in older adults: evidence for a phenotype // J. Gerontol. A Biol. Sci. Med. Sci.– 2001.– Vol. 56.– Р. 146–156. doi:

Gleason L.J., Benton E.A., Alvarez-Nebreda M.L. FRAIL Questionnaire Screening Tool and Short-Term Outcomes in Geriatric Fracture Patients // J. Am. Med. Dir. Assoc.– 2017.– Vol. 18 (12).– Р. 1082–1086. doi:

Guralnik J.M., Ferrucci L., Simonsick E.M. et al. Lower-extremity function in persons over the age of 70 years as a predictor of subsequent disability // New Engl. J. Med.– 1995.– Vol. 332 (9).– Р. 556–561. doi:

Kang M.G., Kim S.W., Yoon S.J. et al. Association between Frailty and hypertension prevalence, treatment, and control in the elderly Korean population // Sci Rep.– 2017.– Vol. 7.– Р. 7542–7563.

Li J., Hu Y.X., Wang W. et al. Chinese Society of Geriatric Hypertension, Chinese Geriatrics Society. Chinese expert consensus on the management of hypertension in the very elderly // J. Geriatr. Cardiol.– 2016.– Vol. 13 (12).– Р. 945–953. doi:

Muller M., Smulders Y.M., de Leeuw P.W. et al. Treatment of hypertension in the oldest old: a critical role for Frailty? // Hypertension.– 2014.– Vol. 63 (3).– Р. 433–441. doi:

Pimenta E., Oparil S. Management of hypertension in the elderly // Nat. Rev. Cardiol.– 2012.– Vol. 9 (5).– P. 286–296. doi:

Puthoff M.L. Outcome measures in cardiopulmonary physical therapy: short physical performance battery // Cardiopulm. Phys. Ther. J.– 2008.– Vol. 19 (1).– Р. 17–22.

Tkacheva O.N., Runikhina N.K., Ostapenko V.S. et al. Prevalence of geriatric syndromes among people aged 65 years and older at four community clinics in Moscow // Clin. Interv. Aging.– 2018.– Vol. 9 (13).– Р. 251–259. doi:

Tomás J.M., Sentandreu-Mañó T., Fernández I. Frailty Status Typologies in Spanish Older Population: Associations with Successful Aging // Int. J. Environ. Res. Public. Health.– 2020.– Vol. 17 (18).– Р. 6772. doi:

Vetrano D.L., Palmer K.M., Galluzzo L. et al. Hypertension and Frailty: a systematic review and meta-analysis // BMJ Open.– 2018.– Vol. 8 (12).– Р. e024406. doi:

Wleklik M., Uchmanowicz I., Jankowska E.A. et al. Multidimensional Approach to Frailty // Front Psychol.– 2020.– Vol. 11.– Р. 564. doi:

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