Біологічні маркери та їх застосування при серцевій недостатності Консенсус Всеукраїнської асоціації кардіологів України, Всеукраїнської асоціації фахівців із серцевої недостатності та Української асоціації фахівців з невідкладної кардіології Робоча група: Л.Г. Воронков, О.Є. Березін (модератори), В.Ю. Жарінова, В.М. Жебель, О.А. Коваль, Ю.С. Рудик, О.М. Пархоменко, В.Й. Целуйко
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Анотація
Наведений консенсус присвячений обговоренню місця і ролі різних підходів до діагностики, стратифікації ризику та індивідуалізованої терапії пацієнтів із серцевою недостатністю (СН), які засновані на визначенні концентрацій біологічних маркерів, що відображають різні патофізіологічні стадії розвитку СН. Практичні рекомендації з використання біологічних маркерів при СН, що є актуальними, були введені з урахуванням категорій доказовості (табл. 1) та сили рекомендацій (табл. 2) після погодженого рішення експертів нашої країни (категорія доказів С), прийнятого на підставі ретельного аналізу даних досліджень у цій галузі. З цією метою опрацьовано дані, опубліковані за останні 5 років у вітчизняній та зарубіжній літературі, а також рекомендації зарубіжних консенсусів з діагностики, прогнозування та лікування гострої і хронічної серцевої недостатності Європейського товариства кардіологів (European Cardiology Society, 2016), Американської колегії кардіологів / Американської серцевої асоціації та Американської асоціації із серцевої недостатності (American College of Cardiology / American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America, 2017).
Консенсус адресований, насамперед, сімейним лікарям, лікарям-терапевтам і кардіологам поліклініки та стаціонарів, анестезіологам, лікарям відділень інтенсивної терапії, клінічним фармакологам, викладачам медичних вищих навчальних закладів, а також лікарям інших спеціальностей. Він може бути основою при розробленні стандартів надання медичної допомоги населенню України. У консенсусі головну увагу приділено практично орієнтованому вибору біологічних маркерів, які мають потужні властивості при встановленні первинного діагнозу СН, прогностичний потенціал при стратифікації хворих із високим ризиком маніфестації СН і прогнозуванні перебігу СН на амбулаторному та госпітальному етапах лікування.
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